According to numerous posts on the official forums the patch has caused resistances such as fire, ice, magic and poisons to become ineffective, with players are complaining that they are taking full damage with resistances active. In a stranger turn of events the patch has caused the dragons of Skyrim to start flying backwards.
EGM’s TAKE: Dragons flying forward are bad enough but flying backwards to, how are we ever going to beat them?!
Source: Bethesda Forum